Please see the Patient Information Guide available at for list of these events. Tell your health care provider about any side effects that bother you or do not go away.
Botox is used in adults to prevent chronic migraine headaches or migraine attacks that occur on 15 or more days per month and that last for at least 4 hours.
There have been postmarketing reports of serious breathing difficulties, including respiratory failure.
The effects of Botox are temporary. Your healthcare provider will tell you how often you will receive your injections, but it is usually not more frequently than every 3 months.
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Botox for medical conditions should only be injected by a trained healthcare provider who can ensure:
An intravesical instillation of diluted local anesthetic with or without sedation, or general anesthesia may be used prior to injection, per local sitio practice. If a local anesthetic instillation is performed, the bladder should be drained and irrigated with sterile saline before injection.
An appropriately sized needle (e.g., 25-30 gauge) may be used for superficial muscles, and a longer 22 gauge needle may be used for deeper musculature. Localization of the involved muscles with techniques such as needle electromyographic guidance, nerve stimulation, or ultrasound is recommended. Repeat BOTOX treatment may be administered when the effect of a previous injection has diminished, but generally no sooner than 12 weeks after the previous injection. The degree and pattern of muscle spasticity at the time of re-injection may necessitate alterations in the dose of BOTOX and muscles to be injected.
The risk of symptoms is probably greatest in children treated for spasticity but symptoms can also occur in adults treated for spasticity and other conditions, particularly in those patients who have an underlying condition that would predispose them to these symptoms. In unapproved uses and in approved indications, cases of spread of effect have been reported radiesse at doses comparable to those used to treat cervical dystonia and spasticity and at lower doses [see Warnings and Precautions (5.1)].
Botox Cosmetic and Botox come as separate products but are both prescription medicines that contain the active ingredient onabotulinumtoxinA. Continue reading
In adult spasticity patients with reduced lung function, upper respiratory tract infections were also reported more frequently as adverse reactions in patients treated with BOTOX than in patients treated with placebo [see Warnings and Precautions (5.10)].
Physicians administering BOTOX must understand the relevant neuromuscular and structural anatomy of the area involved and any alterations to the anatomy due to prior surgical procedures and disease, especially when injecting near the lungs.
Healthcare practitioners should fully familiarize themselves with the product, the product educational materials and the entire package insert.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.